How to destroy mankind with the Plage,Inc Virus in Brutal mode:
Slect from the Gene pool Cytochrome Surge, Teracyte, Translesion+, Creationist, Xerophile.
The secret to kill all mankind is for your disease not to be detected until all humans are infected, and for you to have enough DNA points to Evolve the symptoms and devolve the virus. The Virus is very unstable and will mutate several times, you must have enough DNA points accumulatd to devolve the Virus, because if you don't , the disease will be noticed and the cure will kill it in a macros-econd.
Is very important to at least have 21 DNA points to spare for Virus mutation, it will cost you only 3 DNA points to devolve the Virus mutations, and although we inserted the Creationist gene, which is supposed to slow Virus mutations, as you probably know by now, it does not mean a thing. The Virus will mutate a lot.If your disease is noticed might as well start the game again because you lost.
Step 1: Infect Russia, do not evolve anything, by infecting any country you will get DNA points without you doing nothing, until you get the necessary DNA points to start evolving the symptoms. Remember you need to have a 21 DNA point buffer to devolve the Virus. Go to Abilities and evolve Drug resistance 1, evolve Drug Resistance 2 to infect the rich countries like USA and Canada., . Go to Abilities and Evolve Heat resistance 1, and Heat resistance 2, this will infect the Hotter Countries.
If the planes have filters, evolve go to Transmission and evolve Air 1, and Air 2. This action will infect the planes again. If the ships are using sterilising, go to transmissions and evolve Water 1 and 2. This will infect the ships again.
By now you will realize that the Virus mutates quite often, that is why you most have at least 21 DNA points to devolved the Virus, don't jump the gun, this is a game of patience.
When you get 35 DNA points back up again, go to Transmission and evolve Bird 1, we want the Virus all over the World and Birds are carriers.
This evolutions is all you need to infect the human race.
Save the game now, because it has a tendency to lock up and put the game in fast forward or you will get bored to death waiting on those DNA points..
By the way, now that all the Countries are infected you will not get more infection points. You will get DNA bubbles only. The DNA bubbles will only give 1 to 4 points. This is the boring part, you must accumulate enough DNA points to start evolving your Virus and that is going to take time, be patient, the World must be entirely infected before you take any action.
Don't get frustated because of all the Virus mutations, just keep on devolving them. Remember you have to have at least 70 DNA points to start evolving the symptoms to kill mankind, and this is going to take some time.
After a while you will get a message saying that they are no healthy people left in the World. You have to evolve the symptoms to kill mankind, but at this point you don't have enough DNA points unless you are very lucky, you have to be patient and rack up at least 70 DNA points.
At this point you must be very frustated because the Virus mutates quite often taking away precious DNA away from you,it will seem like you will never get there, but if you are patient, you will see that sooner or later you will get to the 70 DNA points needed.
Once you get 70 DNA points save the game, wait for the next Virus mutation, slow down from fast forward to regular play. Now is time to evolve the Virus. Evolve Coughing, evolve Pneumonia, evolve Pulmonary Oedema, evolve Pulmonary Fibrosis, evolve Total Organ Failure. and to make it harder for the Scientist working on the cure evolve Insomnia, evolve Paranoia, evolve Seizures, evolve Insanity, evolve coma, evolve Anaemia. You need some more DNA points to do that. By now the cure stopped to a crawl.
At this point you Virus will be detected and the World will start working on a cure. As people drop like flys, you will get DNA points, pop the cure bubbles. At this time I would not worry about the cure, put all your DNA on Symptoms, after you get to Paralisys the cure will stop to a crawl.
By this time the cure has stopped and the World is dying.
You will get a message saying that your Virus has destroy humanity.
Victory, you have successfully eliminated life on Earth, you Genetic Mad Scientist.